The Sperm Cell - Production, Maturation, Fertilization, Regeneration (2nd Ed) 9 N0 h% g1 d3 ~4 J& cby Christopher J. De Jonge, Christopher L. R. Barratt + K i8 h f, @Cambridge University Press | July 2017 | ISBN-10: 1107126320 | 316 Pages | PDF | 22.7 mb& A% `9 |8 T" r https://www.amazon.com/Sperm-Cell-Production-Fertilization-Regeneration/dp/1107126320 $ t) B/ Y9 l) w ! D8 h0 J2 T, j! yThis revised and updated second edition provides a comprehensive account of the human male gamete. Detailed overviews of human sperm production, maturation, and function - and how these processes affect and influence fertility, infertility, and assisted reproduction - are given. A wide range of new developments including proteomics, spermatogenesis, sperm-specific WW domain-binding proteins, Ca2+ signalling, DNA packaging, epididymis are explored, whilst a new chapter presents information gained from mouse genetics, highlighting how it informs male fertility research. The impact of environmental factors during pre-pubertal and pubertal stages of life is also investigated. Featuring engaging prose with chapters organized topographically, The Sperm Cell remains an essential resource for andrologists, clinical scientists, and laboratory personnel. ! j( S. H9 x `8 U& q3 x$ H3 t. T" t6 \' v7 e
About the Authors ) I5 O% p( b, n; s6 ?% e9 p# P) h4 RChristopher De Jonge is Director of the Andrology Program at the University of Minnesota Medical Center and Adjunct Professor in the Department of Urology at the University of Minnesota. / l0 N% M6 n( \5 ?6 m1 J; ]7 m& RChristopher L. R. Barratt is Professor of Reproductive Medicine at the School of Medicine, University of Dundee, Ninewells Hospital, Dundee. * v1 x7 F$ a4 _- ]) j, V/ Z) ~$ N9 q+ A* ~; `+ h
CONTENTS% `0 N- p1 B* N) v* k: C* n9 K
List of Contributors page vii % z/ W4 i+ K' r$ ?8 H5 yForeword by Ryuzo Yanagimachi x3 a" R! g6 X) u
Preface xiii 1 _% y3 Q' |& u' Z1 Spermatogenesis: Clinical and Experimental Considerations 1 S& Z# G, A: Y8 R# z2 Sperm Chromatin Stability and Susceptibility to Damage in Relation to Its Structure 214 a6 z0 }- v m: ~
3 Sperm Ultrastructure in Fertile Men and Male Sterility: Revisiting Teratozoospermia 36! [& v6 V8 ~8 j3 Z+ _
4 Sperm RNA and Its Use as a Clinical Marker 59 9 j( r7 z! b0 I2 I! v# j: R. G5 Role of the Epididymis in Sperm Maturation 737 h3 x( [. m e2 T
6 Seminal Plasma Plays Important Roles in Fertility 88 3 U0 r( L; \" \0 O" T& m7 Physiological and Pathological Aspects of SpermMetabolism 109 6 Q. t7 ?) k3 F6 X# P: u, m, V3 u8 Regulation of Sperm Behaviour: The Role(s) of [Ca2+]i Signalling 126/ E) G+ X& {% {% Y
9 Proteomics of Capacitation 143: ~$ q( [$ w/ |1 v6 o" D+ z
10 Current Concepts and Unresolved Questions in Human Sperm Cumulus and Zona Interaction 152 5 J0 v+ W0 E6 g( z. x9 A- U11 Sperm-SpeciicWW-Domain-Binding Proteins 157 X: B; J9 j, ^& o; S2 F. k
12 Fundamental Role for Sperm Phospholipase C in Mammalian Fertilization 177 M* x! a: e' z; q! r
13 Male Infertility and Assisted Reproduction 193 p" W" E& ]3 d- { E( Y$ B
14 The Genetic Basis ofMale Infertility 208 / N* V0 Y& b/ n: D8 C3 L: N5 a! c15 The Sperm Epigenome 230 # p$ l, t7 R1 A! I6 r( B$ z# r16 Environmental Factors andMale Fertility 2405 z1 @/ r: Y8 K- D2 Z2 ]
17 Susceptibility of the Testis to Lifestyle and Environmental Factors During the Life Course 260 7 \: c" t5 S9 R18 Mouse Genetics – How Does It Inform Male Fertility Research? 280 : |- T3 @/ p1 \Index 297 $ x: \+ P$ ?5 B- ]$ L, u$ t4 ]$ _% k1 L% f) [" C/ B. K3 F( q& t
发表于 2017-6-3 18:52:06
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